Document Detail


Treatment of infrabony defects with or without enamel matrix proteins: a 24-month follow-up randomized pilot study.
MedLine Citation:
PMID:  20165744     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate a comparison of open-flap debridement (OFD) with or without the use of enamel matrix proteins (EMP) for the treatment of infrabony defects.
METHOD AND MATERIALS: Ten volunteers (38 infrabony defects) were randomized to receive OFD+EMP (test site) and OFD (control site). Clinical outcomes included mean changes in Plaque Index, Gingival Index, probing pocket depth (PPD), relative attachment level (RAL), gingival recession, width of keratinized tissue, and dental mobility at baseline and at 24 months.
RESULTS: A significant reduction of 4.21+/-0.97 mm was observed in PPD for the OFD+EMP group (from 6.30+/-0.99 mm to 2.09+/-0.97 mm) and of 3.28+/-1.23 mm for the OFD group (from 6.13+/-0.88 mm to 2.85+/-1.42 mm) (P<.001). The reduction in PPD was statistically significantly greater for OFD+EMP compared to OFD (P=.03). The mean RAL decreased from 13.26+/-1.88 mm to 7.57+/-2.05 mm for the OFD+EMP group (a gain of 5.69+/-1.96 mm) and from 13.37+/-1.71 mm to 8.13+/-1.34 mm (P<.001) for the OFD group (a gain of 5.24+/-1.55 mm). Gingival recession was higher in the OFD+EMP group than in the OFD group. The mean keratinized tissue significantly decreased from 4.41+/-1.39 mm to 3.63+/-1.54 mm for OFD flap group (P<.01).
CONCLUSION: Both treatment modalities were efficient in improving RAL and PPD. Within groups, there was a significant reduction in keratinized tissue for OFD and a significant postoperative recession for the OFD + EMP group. Infrabony defects treated with OFD + EMP showed significantly more PPD reduction when compared to OFD.
Authors:
Daniella Chambrone; Ivan Munhoz Pasin; Leandro Chambrone; Claudio Mendes Pannuti; Marina Clemente Conde; Luiz A Lima
Related Documents :
7569024 - Reproducibility of patient positioning during routine radiotherapy, as assessed by an i...
12797574 - Treatment of cervical sensitivity with a root sealant.
11453234 - Effects of pretreatment clinical parameters on bioactive glass implantation in intrabon...
20171354 - Comparison of classic endodontic techniques versus contemporary techniques on endodonti...
24192474 - Circumcision: perspective in a nigerian teaching hospital.
10064634 - Postoperative hemorrhage after tonsillectomy: use of ketorolac tromethamine.
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Quintessence international (Berlin, Germany : 1985)     Volume:  41     ISSN:  1936-7163     ISO Abbreviation:  Quintessence Int     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-18     Completed Date:  2010-11-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0342677     Medline TA:  Quintessence Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  125-34     Citation Subset:  D    
Affiliation:
Department of Stomatology, School of Dentistry, University of São Paulo, São Paulo, Brazil. chambrone@usp.br
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Alveolar Bone Loss / surgery,  therapy*
Bone Regeneration
Chronic Periodontitis / surgery,  therapy*
Dental Enamel Proteins / therapeutic use*
Female
Gingival Recession / etiology,  surgery,  therapy
Humans
Male
Matched-Pair Analysis
Middle Aged
Periodontal Attachment Loss / surgery,  therapy
Periodontal Debridement* / adverse effects
Periodontal Pocket / surgery,  therapy
Pilot Projects
Statistics, Nonparametric
Treatment Outcome
Chemical
Reg. No./Substance:
0/Dental Enamel Proteins; 0/enamel matrix proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Relationship between crowns and the periodontium: a literature update.
Next Document:  Influence of white and gray endodontic posts on color changes of tooth roots, composite cores, and a...