Document Detail


Treatment of incomplete abortion and miscarriage with misoprostol.
MedLine Citation:
PMID:  17961569     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A literature review was conducted to determine whether misoprostol is an effective treatment for incomplete abortion and, if so, to recommend an appropriate regimen. All English language articles published before October 2007 using misoprostol in at least one of the study arms were reviewed to determine the efficacy of misoprostol when used to treat incomplete abortion in the first trimester. All available unpublished data previously presented at international scientific meetings were also reviewed. Sufficient evidence was found in support of misoprostol as a safe and effective means of non-surgical uterine evacuation. A single dose of misoprostol 600 microg oral is recommended for treatment of incomplete abortion in women presenting with a uterine size equivalent to 12 weeks gestation.
Authors:
J Blum; B Winikoff; K Gemzell-Danielsson; P C Ho; R Schiavon; A Weeks
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2007-10-24
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  99 Suppl 2     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-11-20     Completed Date:  2008-03-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  S186-9     Citation Subset:  IM    
Affiliation:
Gynuity Health Projects, New York, NY 10010, USA. jblum@gynuity.org
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MeSH Terms
Descriptor/Qualifier:
Abortifacient Agents, Nonsteroidal / administration & dosage*
Abortion, Incomplete / diagnosis,  drug therapy*
Abortion, Spontaneous / diagnosis,  drug therapy*
Administration, Oral
Administration, Sublingual
Female
Humans
Misoprostol / administration & dosage*
Pregnancy
Chemical
Reg. No./Substance:
0/Abortifacient Agents, Nonsteroidal; 59122-46-2/Misoprostol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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