Document Detail


Treatment of idiopathic sclerosing inflammation of the orbit (myositis) with infliximab.
MedLine Citation:
PMID:  18631325     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: We report the successful use of infliximab in a young patient with idiopathic sclerosing orbital inflammation (myositis). METHODS: We describe the patient's medical records and review the literature. RESULTS: Idiopathic myositis in this patient could not be satisfactorily treated with corticosteroids or chemotherapy. Biopsy showed sclerosing orbital inflammation. The patient had a prompt and sustained response with infliximab and methotrexate treatment. CONCLUSIONS: Infliximab and methotrexate might be considered in patients with idiopathic sclerosing orbital inflammation (myositis).
Authors:
Sven Sahlin; B?rje Lignell; Maria Williams; Maryam Dastmalchi; Abiel Orrego
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta ophthalmologica     Volume:  87     ISSN:  1755-3768     ISO Abbreviation:  Acta Ophthalmol     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-12-16     Completed Date:  2010-02-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101468102     Medline TA:  Acta Ophthalmol     Country:  England    
Other Details:
Languages:  eng     Pagination:  906-8     Citation Subset:  IM    
Affiliation:
St Erik's Eye Hospital, Karolinska Institute, Stockholm, Sweden. sven.sahlin@sankterik.se
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adrenal Cortex Hormones / therapeutic use
Antibodies, Monoclonal / therapeutic use*
Drug Therapy, Combination
Female
Humans
Magnetic Resonance Imaging
Methotrexate / therapeutic use*
Orbital Myositis / diagnosis,  drug therapy*,  pathology*
Retreatment
Sclerosis
Treatment Failure
Chemical
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Antibodies, Monoclonal; 0/infliximab; 59-05-2/Methotrexate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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