| Treatment of hypoxemia during xylazine-tiletamine-zolazepam immobilization of wapiti. | |
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MedLine Citation:
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PMID: 11708204 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hypoxemia is a commonly observed complication during the chemical immobilization of wild ruminants. If severe and left untreated, it can predispose animals to arrhythmias, organ failure, and capture myopathy. The following prospective study was designed to measure the degree of hypoxemia in wapiti that were immobilized with a combination of xylazine and tiletamine-zolazepam and to assess the response to nasal oxygen therapy. Pulse oximetry and arterial blood gas analysis were used to assess the degree of hypoxemia prior to nasal insufflation of oxygen and to demonstrate any beneficial effects of this intervention. All wapiti exhibited mild to marked hypoxemia (PaO2 = 43 +/- 11.8 mmHg) prior to treatment and showed marked improvement after 5 minutes of nasal insufflation of oxygen at 10 L/min (PaO2 = 207 +/- 60 mmHg). This inexpensive, noninvasive technique has great benefit in treating clinical hypoxemia under field conditions, and we recommend that nasal insufflation of oxygen be implemented during xylazine-tiletamine-zolazepam-induced immobilization of wapiti and other wild ruminants. |
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Authors:
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M R Read; N A Caulkett; A Symington; T K Shury |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Canadian veterinary journal. La revue vétérinaire canadienne Volume: 42 ISSN: 0008-5286 ISO Abbreviation: Can. Vet. J. Publication Date: 2001 Nov |
Date Detail:
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Created Date: 2001-11-15 Completed Date: 2002-03-21 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0004653 Medline TA: Can Vet J Country: Canada |
Other Details:
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Languages: eng Pagination: 861-4 Citation Subset: IM |
Affiliation:
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Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic alpha-Agonists
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adverse effects Anesthetics, Dissociative / adverse effects Animals Animals, Wild Anoxia / chemically induced, drug therapy, veterinary* Anti-Anxiety Agents / adverse effects Benzodiazepines Blood Gas Analysis / veterinary Deer* Drug Combinations Female Heart Rate / drug effects Immobilization* / adverse effects Male Oxygen / administration & dosage*, blood Prospective Studies Respiration / drug effects Tiletamine / adverse effects Xylazine / adverse effects Zolazepam / adverse effects |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic alpha-Agonists; 0/Anesthetics, Dissociative; 0/Anti-Anxiety Agents; 0/Drug Combinations; 12794-10-4/Benzodiazepines; 14176-49-9/Tiletamine; 31352-82-6/Zolazepam; 7361-61-7/Xylazine; 7782-44-7/Oxygen |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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