Document Detail


Treatment of hypertension.
MedLine Citation:
PMID:  9125800     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Effectiveness of antihypertensive agents is assessed not only by systemic blood pressure levels, but by multiple parameters that reflect specific organ functions. Among antihypertensive agents, those which inhibit angiotensin actions show particular efficacy in ameliorating end organ damage. This efficacy likely reflects the central role that angiotensin has in regulating renal function by its multifaceted actions. We will therefore focus on the renin angiotensin system, and compare its actions on parameters of renal injury with other antihypertensive treatment approaches.
Authors:
A Fogo; V Kon
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Seminars in nephrology     Volume:  16     ISSN:  0270-9295     ISO Abbreviation:  Semin. Nephrol.     Publication Date:  1996 Nov 
Date Detail:
Created Date:  1997-05-20     Completed Date:  1997-05-20     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8110298     Medline TA:  Semin Nephrol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  555-66     Citation Subset:  IM    
Affiliation:
Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232-2165, USA.
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MeSH Terms
Descriptor/Qualifier:
Angiotensin-Converting Enzyme Inhibitors / therapeutic use*
Animals
Antihypertensive Agents / administration & dosage,  therapeutic use*
Glomerular Filtration Rate
Humans
Hypertension / complications,  diagnosis,  drug therapy*
Kidney Diseases / complications,  diagnosis,  drug therapy*
Kidney Glomerulus / drug effects*,  pathology
Prognosis
Grant Support
ID/Acronym/Agency:
DK 42159/DK/NIDDK NIH HHS; DK 44757/DK/NIDDK NIH HHS
Chemical
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors; 0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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