| Treatment of hypertension in hemodialysis patients with nifedipine. | |
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MedLine Citation:
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PMID: 6345369 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The hemodynamic effects of nifedipine were studied in nine patients with acute or chronic renal failure undergoing hemodialysis. Arterial blood pressure was lowered within 15 minutes of oral administration of nifedipine 10 mg. Mean arterial pressure and total systemic peripheral resistance were significantly decreased, whereas cardiac index and heart rate revealed slight but statistically insignificant changes. Changes in pulmonary artery diastolic pressure and mean right atrial pressure which were closely related to cardiac preload were not significant. However, the antihypertensive effect was enhanced in patients with lower pretreatment preload. Results show that oral nifedipine is effective in rapidly reducing blood pressure during or following hemodialysis. |
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Authors:
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K Kubo; K Shiraishi; H Muto; T Suzuki; N Sugino |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Hypertension Volume: 5 ISSN: 0194-911X ISO Abbreviation: Hypertension Publication Date: 1983 Jul-Aug |
Date Detail:
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Created Date: 1983-08-26 Completed Date: 1983-08-26 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7906255 Medline TA: Hypertension Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: II109-12 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antihypertensive Agents / therapeutic use Female Hemodynamics / drug effects Humans Hypertension / complications, drug therapy* Kidney Failure, Chronic / complications, therapy* Kidney Transplantation Male Nifedipine / therapeutic use* Pyridines / therapeutic use* Renal Dialysis* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents; 0/Pyridines; 21829-25-4/Nifedipine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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