Document Detail


Treatment of hyperkeratosis with Kerafoam emollient foam (30% urea) to assess effectiveness and safety within a clinical setting: a case study report.
MedLine Citation:
PMID:  18335652     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ten patients enrolled in a single center, observational, prospective, open-label case study to assess the effectiveness and safety of a 28 day regimen with Kerafoam 30% urea emollient foam for treatment of hyperkeratosis. Clinician assessments of skin condition were recorded at baseline, day 14, and day 28. In addition, patients' ratings of the treatment impact on quality of life and skin condition, as well as overall satisfaction with the product were obtained. Key results demonstrated significant improvements in clinicians' ratings of skin condition at the day 14 and day 28 visits compared to baseline and significant improvements in patients' ratings of quality of life. No adverse events were reported and all patients completed the 28-day treatment regimen. Patient and clinician evaluations of the 30% urea emollient foam product were extremely favorable.
Authors:
Jay A Goldstein; Ronald M Gurge
Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of drugs in dermatology : JDD     Volume:  7     ISSN:  1545-9616     ISO Abbreviation:  J Drugs Dermatol     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-03-13     Completed Date:  2008-05-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101160020     Medline TA:  J Drugs Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  159-62     Citation Subset:  IM    
Affiliation:
jaygoldsteinmd@aol.com
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MeSH Terms
Descriptor/Qualifier:
Administration, Cutaneous
Adult
Aged
Aged, 80 and over
Dose-Response Relationship, Drug
Drug Administration Schedule
Emollients / administration & dosage,  chemistry,  therapeutic use*
Female
Humans
Hyperkeratosis, Epidermolytic / drug therapy*,  pathology
Male
Middle Aged
Patient Satisfaction / statistics & numerical data
Prospective Studies
Quality of Life
Severity of Illness Index
Skin / drug effects*,  pathology
Time Factors
Treatment Outcome
Urea / administration & dosage,  chemistry,  therapeutic use*
Chemical
Reg. No./Substance:
0/Emollients; 57-13-6/Urea

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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