Document Detail


Treatment of hypercalcemia.
MedLine Citation:
PMID:  6337798     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The indications, effectiveness, and adverse effects of the numerous treatment modalities for hypercalcemia are presented. Results of a retrospective chart review of 72 admissions (53 patients) for hypercalcemia-related diseases are presented to emphasize the therapeutic principles that should be applied in the management of these patients. Hydration, forced diuresis, oral phosphates, and glucocorticosteroid drugs are common therapeutic approaches. Combination therapy with glucocorticosteroid drugs, oral phosphates, and forced diuresis is utilized to take advantage of multiple mechanisms of action. Outpatient therapy for hypercalcemia consists primarily of glucocorticosteroid agents and oral phosphates. Most patients are treated if the serum calcium level is greater than or equal to 12 mg/dL. An algorithm is presented to assist the clinician in selecting the most efficacious treatment plan.
Authors:
G T Elliott; M W McKenzie
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Drug intelligence & clinical pharmacy     Volume:  17     ISSN:  0012-6578     ISO Abbreviation:  Drug Intell Clin Pharm     Publication Date:  1983 Jan 
Date Detail:
Created Date:  1983-04-07     Completed Date:  1983-04-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0212457     Medline TA:  Drug Intell Clin Pharm     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  12-22     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Calcium / blood
Chelating Agents / therapeutic use
Diuresis
Diuretics / therapeutic use
Female
Humans
Hypercalcemia / drug therapy*,  etiology
Indomethacin / therapeutic use
Male
Mineralocorticoids / therapeutic use
Phosphates / therapeutic use
Renal Dialysis
Serum Albumin / metabolism
Chemical
Reg. No./Substance:
0/Chelating Agents; 0/Diuretics; 0/Mineralocorticoids; 0/Phosphates; 0/Serum Albumin; 53-86-1/Indomethacin; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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