| Treatment of glaucoma in children with Sturge-Weber syndrome. | |
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MedLine Citation:
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PMID: 10714693 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Sturge-Weber syndrome is a rare congenital neuro-oculocutaneous disorder. Ocular involvement can include glaucoma and vascular malformations of the conjunctiva, episclera, choroid, and retina. METHODS: The records of 19 Sturge-Weber syndrome patients (mean age 8.2 years) treated at our institution were reviewed to determine the incidence of ophthalmologic manifestations in Sturge-Weber syndrome. RESULTS: Glaucoma occurred in 42% of all patients and was more frequent in patients with a port-wine stain involving both upper and lower eyelids. Other ocular manifestations included conjunctival/episcleral hemangioma, choroidal hemangioma, iris heterochromia, retinal detachment, strabismus, and homonymous hemianopia. In 7 of 8 patients with glaucoma, topical pharmacotherapy (beta-blockers and carbonic anhydrase inhibitors) alone failed to normalize intraocular pressures. In those patients, cryocoagulation of the ciliary body was performed. Mean postoperative intraocular pressure after a mean follow-up of 4-5 years was <22 mm Hg in 6 patients. CONCLUSIONS: Cryocoagulation of the ciliary body combined with topical medication is an effective and safe treatment option in the management of glaucoma in children with Sturge-Weber syndrome. |
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Authors:
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C van Emelen; M Goethals; L Dralands; I Casteels |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of pediatric ophthalmology and strabismus Volume: 37 ISSN: 0191-3913 ISO Abbreviation: J Pediatr Ophthalmol Strabismus Publication Date: 2000 Jan-Feb |
Date Detail:
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Created Date: 2000-03-27 Completed Date: 2000-03-27 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7901143 Medline TA: J Pediatr Ophthalmol Strabismus Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 29-34 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, University Hospitals Leuven, Katholieke Universiteit, Belgium. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adrenergic beta-Antagonists / administration & dosage, therapeutic use* Adult Carbonic Anhydrase Inhibitors / administration & dosage, therapeutic use* Child Child, Preschool Ciliary Body / surgery* Cryosurgery* Drug Therapy, Combination Eye Diseases / etiology Female Glaucoma / etiology, surgery* Humans Infant Intraocular Pressure Male Retrospective Studies Sturge-Weber Syndrome / complications* |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Carbonic Anhydrase Inhibitors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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