Document Detail

Treatment of giant Bowen's disease with sequential use of photodynamic therapy and imiquimod cream.
MedLine Citation:
PMID:  21535173     Owner:  NLM     Status:  In-Data-Review    
We present a 79-year-old man with a 2-year history of Bowen's disease. The 10 × 10 plaque was located on the right frontotemporal area. The patient was treated with two photodynamic therapy (PDT) sessions, performed 1 week apart, followed by five times per week application of imiquimod 5% cream for 6 consecutive weeks. Complete clinical and histological response was achieved 3 months after treatment was completed. The patient remains recurrence free 12 months after treatment. Cosmetic outcome was evaluated as fair because of residual erythema. Long-term follow-up is mandatory for assessment of recurrences. Further studies are needed in order to confirm the improved outcome using the combination of PDT and imiquimod cream.
Eleni Sotiriou; Aimilios Lallas; Zoi Apalla; Demetris Ioannides
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Photodermatology, photoimmunology & photomedicine     Volume:  27     ISSN:  1600-0781     ISO Abbreviation:  Photodermatol Photoimmunol Photomed     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9013641     Medline TA:  Photodermatol Photoimmunol Photomed     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  164-6     Citation Subset:  IM    
Copyright Information:
© 2011 John Wiley & Sons A/S.
First Dermatologic Department, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece State Hospital for Skin and Venereal Diseases, Thessaloniki, Greece.
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