| Treatment of gastric ulcer. What is old and what is new. | |
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MedLine Citation:
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PMID: 6337574 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The rational treatment of gastric ulcer (GU) requires both an understanding of the various causative factors responsible for what is best considered a spectrum of disorders, as well as a familiarity with the newer antisecretory and cytoprotective therapies that are available. Gastric ulcers that fulfill the criteria to be peptic ulcers (ie, occur in the antrum in the presence of excess luminal acid, with or without a coexisting duodenal ulcer) are best treated with a histamine H2-receptor antagonist. For GUs that develop in the setting of normal or reduced acid output, or those that occur as a result of direct (ie, drug-induced or bile acid-related) mucosal injury, use of a cytoprotective agent (eg, sucralfate) is the treatment of choice. Any GU that fails to heal within 12 to 15 weeks should be carefully examined to exclude the presence of a malignant neoplasm and should be considered for surgical resection. |
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Authors:
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J H Lewis |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Archives of internal medicine Volume: 143 ISSN: 0003-9926 ISO Abbreviation: Arch. Intern. Med. Publication Date: 1983 Feb |
Date Detail:
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Created Date: 1983-03-11 Completed Date: 1983-03-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372440 Medline TA: Arch Intern Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 264-74 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antacids / therapeutic use Female Hospitalization Humans Hypnotics and Sedatives / therapeutic use Male Middle Aged Recurrence Stomach Ulcer / diagnosis, drug therapy, epidemiology, etiology, therapy* |
| Chemical | |
Reg. No./Substance:
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0/Antacids; 0/Hypnotics and Sedatives |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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