Document Detail

Treatment of female pattern hair loss with a combination of spironolactone and minoxidil.
MedLine Citation:
PMID:  17222303     Owner:  NLM     Status:  MEDLINE    
A 53-year-old woman with clinical evidence of female pattern hair loss and histological evidence of androgenetic alopecia was initially treated with the oral antiandrogen spironolactone 200 mg daily. Serial scalp photography documented hair regrowth at 12 months; however, the hair regrowth plateaued, and at 24 months there had been no further improvement in hair density. Twice daily therapy with topical minoxidil 5% solution was then introduced and further regrowth documented, confirming the additive effect of combination therapy.
Carlijn Hoedemaker; Sylvia van Egmond; Rodney Sinclair
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Australasian journal of dermatology     Volume:  48     ISSN:  0004-8380     ISO Abbreviation:  Australas. J. Dermatol.     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-01-15     Completed Date:  2007-03-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0135232     Medline TA:  Australas J Dermatol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  43-5     Citation Subset:  IM    
Department of Dermatology, St Vincent's Hospital, University of Melbourne, Melbourne, Victoria, Australia.
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MeSH Terms
Administration, Cutaneous
Administration, Oral
Aldosterone Antagonists / administration & dosage,  therapeutic use*
Alopecia / diagnosis*,  drug therapy*,  pathology
Drug Therapy, Combination
Middle Aged
Minoxidil / administration & dosage,  therapeutic use*
Spironolactone / administration & dosage,  therapeutic use*
Vasodilator Agents / administration & dosage,  therapeutic use*
Reg. No./Substance:
0/Aldosterone Antagonists; 0/Vasodilator Agents; 38304-91-5/Minoxidil; 52-01-7/Spironolactone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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