Document Detail

Treatment of facial spasm with Oculinum (C. botulinum toxin).
MedLine Citation:
PMID:  3772688     Owner:  NLM     Status:  MEDLINE    
Forty-six consecutive adult patients with facial spasm were treated with one or more Botulinum toxin (Oculinum) injections to control muscle spasm. During the follow-up period of 6.6 months (one week-12 months), 27 patients required retreatment with a mean time interval of 3.4 months between treatments. Control of facial spasm was achieved in all patients. Complications included occasional bruising around the injection site and a transient blepharoptosis in one patient. No systemic effect was observed. This preliminary report suggests that treatment with Botulinum toxin (Oculinum) is an acceptable alternative to surgical management in select patients.
A W Biglan; M May
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of pediatric ophthalmology and strabismus     Volume:  23     ISSN:  0191-3913     ISO Abbreviation:  J Pediatr Ophthalmol Strabismus     Publication Date:    1986 Sep-Oct
Date Detail:
Created Date:  1986-12-12     Completed Date:  1986-12-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7901143     Medline TA:  J Pediatr Ophthalmol Strabismus     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  216-21     Citation Subset:  IM    
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MeSH Terms
Aged, 80 and over
Botulinum Toxins / adverse effects,  therapeutic use*
Drug Evaluation
Eyelid Diseases / chemically induced
Facial Muscles*
Middle Aged
Spasm / drug therapy*
Reg. No./Substance:
0/Botulinum Toxins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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