Document Detail


Treatment of epileptogenic cavernomas: surgery versus radiosurgery.
MedLine Citation:
PMID:  17536202     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Epilepsy is the most common symptom of cavernoma. Although microsurgery is the mainstay treatment for epileptogenic cavernoma, this procedure may cause severe complications for some lesions. This report aimed to study if linear accelerator (LINAC) radiosurgery was an alternative treatment modality for epileptogenic cavernoma. METHODS: In this retrospective study, 29 patients were diagnosed with epileptogenic cavernomas from September 1995 to March 2005. Fifteen patients were treated with surgical excision and 14 with LINAC radiosurgery. The evaluation of epilepsy control was according to Engel's classification. RESULTS: In the surgical group, 13 (86.7%) of 15 patients had a class I seizure-free outcome. In the radiosurgery group, class I control was achieved in 9 (64.3%) of 14 patients. However, there was no significant difference in the results of treatment between the two groups. CONCLUSIONS: LINAC radiosurgery is an alternative treatment for epileptogenic cavernomas, especially when the lesions are located in the central regions or eloquent areas of the brain.
Authors:
Peng-Wei Hsu; Cheng-Nen Chang; Chen-Kan Tseng; Kuo-Cheng Wei; Chun-Chieh Wang; Chi-Cheng Chuang; Yin-Cheng Huang
Publication Detail:
Type:  Journal Article     Date:  2007-05-23
Journal Detail:
Title:  Cerebrovascular diseases (Basel, Switzerland)     Volume:  24     ISSN:  1015-9770     ISO Abbreviation:  Cerebrovasc. Dis.     Publication Date:  2007  
Date Detail:
Created Date:  2007-07-13     Completed Date:  2007-08-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9100851     Medline TA:  Cerebrovasc Dis     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  116-20; discussion 121     Citation Subset:  IM    
Affiliation:
Brain Division of Neurosurgery, Department of Surgery, Chang Gung Memorial Hospital, Tao Yuan, Taiwan, ROC.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Brain Neoplasms / complications,  surgery*
Epilepsy / etiology*,  surgery
Female
Follow-Up Studies
Hemangioma, Cavernous, Central Nervous System / complications,  surgery*
Humans
Male
Microsurgery*
Middle Aged
Neurosurgical Procedures / instrumentation,  methods*
Radiosurgery* / instrumentation
Retrospective Studies
Severity of Illness Index
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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