| Treatment emergent mania responding to valproate in a Chinese female adolescent population with eating disorders: a case series. | |
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MedLine Citation:
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PMID: 18567063 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Eating disorders are commonly associated with depressive symptoms. In an adolescent and binge eating population fluoxetine is commonly used to treat co-morbid depression associated with eating disorders. In some patients this may precipitate treatment emergent mania (TEM). Risk factors in the adolescent population include being older, female, having a longer duration of illness, more previous mood episodes, a higher prevalence of subclinical hypothyroidism, early-onset anxiety and recent exposure to a mood-elevating agent. Diagnosis and management of these co-morbid conditions is challenging due to the overlapping symptomatology and the adverse effects of both conditions complicating pharmacological management. This is illustrated with three cases in a Chinese female adolescent population that experienced TEM while on fluoxetine and responded to valproate. |
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Authors:
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Phern Chern Tor; Ee Lian Lee |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: European eating disorders review : the journal of the Eating Disorders Association Volume: 16 ISSN: 1099-0968 ISO Abbreviation: Eur Eat Disord Rev Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-10-29 Completed Date: 2008-12-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9436977 Medline TA: Eur Eat Disord Rev Country: England |
Other Details:
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Languages: eng Pagination: 421-6 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, Singapore General Hospital, Singapore. torphernchern@gmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Anorexia Nervosa / complications, drug therapy* Anticonvulsants / therapeutic use Antimanic Agents / therapeutic use Bipolar Disorder / etiology*, therapy* Bulimia Nervosa / complications, drug therapy* Eating Disorders / complications*, psychology* Female Humans Isoxazoles / therapeutic use Male Phenytoin / therapeutic use Risk Factors Sex Characteristics Singapore Valproic Acid / therapeutic use* Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Anticonvulsants; 0/Antimanic Agents; 0/Isoxazoles; 57-41-0/Phenytoin; 68291-97-4/zonisamide; 99-66-1/Valproic Acid |
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