Document Detail

Treatment efficacy of intermittent claudication by surgical intervention, supervised physical exercise training compared to no treatment in unselected randomised patients I: one year results of functional and physiological improvements.
MedLine Citation:
PMID:  11472042     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: to compare the effect of surgery, exercise and simple observation on maximum exercise power in claudicants.
DESIGN: prospective, randomised study.
METHODS: a total of 264 unselected claudicants were randomised to supervised exercise training, invasive treatment (open surgical or endovascular procedures) or observation. One year treatment outcomes were analysed on an intention to-treat basis.
RESULTS: invasively treated patients showed a significant improvement in maximum walking power, stopping distance, post-ischaemic blood flow and big toe pressure at one year. Patients randomised to physical exercise training or to the control group did not improve in any outcome measure.
CONCLUSION: invasive treatment increased walking capacity, leg blood pressure and flow. Supervised physical exercise training offered no therapeutic advantage compared to untreated controls.
J Gelin; L Jivegård; C Taft; J Karlsson; M Sullivan; A G Dahllöf; R Sandström; B Arfvidsson; K Lundholm
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery     Volume:  22     ISSN:  1078-5884     ISO Abbreviation:  Eur J Vasc Endovasc Surg     Publication Date:  2001 Aug 
Date Detail:
Created Date:  2001-07-26     Completed Date:  2001-08-30     Revised Date:  2014-07-28    
Medline Journal Info:
Nlm Unique ID:  9512728     Medline TA:  Eur J Vasc Endovasc Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  107-13     Citation Subset:  IM    
Copyright Information:
Copyright 2001 Harcourt Publishers Limited.
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MeSH Terms
Aged, 80 and over
Exercise Test
Follow-Up Studies
Intermittent Claudication / surgery*
Middle Aged
Prospective Studies
Quality of Life
Treatment Outcome

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