Document Detail

Treatment of dermatitis from parthenin.
MedLine Citation:
PMID:  4042647     Owner:  NLM     Status:  MEDLINE    
Composites and some other plants containing sesquiterpene lactones, frequently cause allergic contact dermatitis in man. No treatment is available to control this disease successfully. We have used an amino acid, cysteine, to treat allergic contact dermatitis in guinea pigs sensitized to parthenin, a major sesquiterpene lactone of an allergenic weed, Parthenium hysterophorus L. Cysteine treatment of the allergic reaction induced by parthenin resulted in (a) reduced time of recovery and (b) reduced intensity of the skin reaction.
J Picman; A K Picman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Contact dermatitis     Volume:  13     ISSN:  0105-1873     ISO Abbreviation:  Contact Derm.     Publication Date:  1985 Jul 
Date Detail:
Created Date:  1985-11-14     Completed Date:  1985-11-14     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7604950     Medline TA:  Contact Dermatitis     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  9-13     Citation Subset:  IM    
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MeSH Terms
Administration, Topical
Cysteine / therapeutic use*
Dermatitis, Contact / drug therapy*,  etiology
Guinea Pigs
Sesquiterpenes / adverse effects*
Reg. No./Substance:
0/Sesquiterpenes; 508-59-8/parthenin; 52-90-4/Cysteine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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