| Treatment of crack cocaine use with carbamazepine. | |
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MedLine Citation:
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PMID: 1314015 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Crack is a rock crystalline alkaloid form of cocaine which can be smoked. At the University of Minnesota, we have developed an experimental pharmacologic treatment for cocaine abusers. Of 26 patients treated to date, 16 have been crack cocaine users. During the hundred days preceding treatment, the 16 crack subjects used cocaine by all routes an average of 71 days each. Improvement was based on a self-reported decrease in cocaine frequency of use. Using carbamazepine, seven highly successful and six partially successful patients reduced their use to 0.7 days and 26 days per 100 days, respectively. These results, though hopeful, must be viewed with caution and considered preliminary and tentative. |
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Authors:
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J A Halikas; K L Kuhn; F S Crea; G A Carlson; R Crosby |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of drug and alcohol abuse Volume: 18 ISSN: 0095-2990 ISO Abbreviation: Am J Drug Alcohol Abuse Publication Date: 1992 |
Date Detail:
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Created Date: 1992-05-11 Completed Date: 1992-05-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7502510 Medline TA: Am J Drug Alcohol Abuse Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 45-56 Citation Subset: IM |
Affiliation:
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University of Minnesota School of Medicine, Minneapolis. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Carbamazepine / therapeutic use* Crack Cocaine* / adverse effects Day Care Female Follow-Up Studies Heroin Dependence / rehabilitation Humans Male Methadone / therapeutic use Substance Abuse Treatment Centers Substance Abuse, Intravenous / rehabilitation Substance Withdrawal Syndrome / rehabilitation Substance-Related Disorders / rehabilitation* |
| Chemical | |
Reg. No./Substance:
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0/Crack Cocaine; 298-46-4/Carbamazepine; 76-99-3/Methadone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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