| Treatment of coronary in-stent restenosis with a novel paclitaxel urea coated balloon. | |
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MedLine Citation:
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PMID: 20948504 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Randomized clinical trials investigating the treatment of coronary in-stent restenosis with paclitaxel iopromide coated balloon catheters have shown favorable results. The aim of the present clinical investigation was to assess the efficacy of a novel paclitaxel urea coated angioplasty balloon in the treatment of coronary in-stent restenosis. A total of 26 restenotic bare metal stents in 23 patients with a lesion length of 22.8±11.1 mm and a reference vessel diameter of 2.64±0.31 mm were treated. Up to six months and including the six-month angiographic control, only one target lesion revascularization was necessary; in total, the rate of major adverse cardiovascular events until six-month follow-up was 4.3 %. In-stent late lumen loss was 0.07±0.37 mm, in-segment late lumen loss 0.02±0.50 mm. Binary restenosis was present in one patient (4.3%). The results of this first-in-human series with a paclitaxel urea coated balloon are comparable to paclitaxel iopromide coated balloon catheters. Randomized, controlled clinical trials are warranted to further evaluate this promising approach. |
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Authors:
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B Cremers; Y Clever; S Schaffner; U Speck; M Böhm; B Scheller |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Minerva cardioangiologica Volume: 58 ISSN: 0026-4725 ISO Abbreviation: Minerva Cardioangiol Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0400725 Medline TA: Minerva Cardioangiol Country: Italy |
Other Details:
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Languages: eng Pagination: 583-8 Citation Subset: IM |
Affiliation:
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Clinic of Internal Medicine III, Saarland University Hospital, Homburg/Saar, Germany - bruno.scheller@uks.eu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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