| Treatment of chronic femoral osteomyelitis with platelet-rich plasma (PRP): a case report. | |
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MedLine Citation:
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PMID: 18343727 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Chronic osteomyelitis is a serious problem in developing countries. A lot of patients with chronic osteomyelitis have to be treated for a very long period and get several operations including complete debridement, antibiotic bead implant, bone grafts, etc. However, traditional methods seem to be ineffective in some patients, who always have a high incidence of recurrence. We report a case of chronic osteomyelitis in bilateral femurs, which has been treated with long time antibiotic therapy, about twenty debridements, yet the sinus remained unhealed for over four years. At the end of this period, we used PRP to treat the unhealed sinus and obtained good results. Though the mechanism by which PRP treats chronic osteomyelitis is now unclear, the results encourage study further. |
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Authors:
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Ting Yuan; Changqing Zhang; Bingfang Zeng |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2008-03-17 |
Journal Detail:
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Title: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis Volume: 38 ISSN: 1473-0502 ISO Abbreviation: Transfus. Apher. Sci. Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-04-30 Completed Date: 2008-07-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101095653 Medline TA: Transfus Apher Sci Country: England |
Other Details:
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Languages: eng Pagination: 167-73 Citation Subset: T |
Affiliation:
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Orthopaedic Department, Shanghai Sixth People's Hospital, Shanghai Jiaotong University, Shanghai, China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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pharmacology Chronic Disease Femur / microbiology, pathology*, radiography Humans Intercellular Signaling Peptides and Proteins Male Methicillin Resistance Middle Aged Osteomyelitis / therapy* Platelet-Rich Plasma / metabolism* Staphylococcus aureus / metabolism Time Factors Tomography, X-Ray Computed / methods Treatment Outcome Wound Healing |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Intercellular Signaling Peptides and Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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