Document Detail

Treatment of bleeding gastroduodenal ulcer
MedLine Citation:
PMID:  17484823     Owner:  NLM     Status:  MEDLINE    
Of 1700 patients (31/100,000 inhabitants) with endoscopically verified bleeding gastroduodenal ulcer registered yearly in Denmark, 20% rebled, 8% had surgery, and 11% died. Forrest Ia-IIb ulcers are treated endoscopically with combined or thermal methods. Monotherapy with epinephrine is insufficient. The effect of tranexamic acid is uncertain. Proton pump inhibitors reduce rebleeding and surgery but not mortality. H. Pylori should be diagnosed and eradicated in order to reduce recurrence. Second look gastroscopy should be used for selected cases only. Treatment by dedicated teams may be beneficial.
Sven Adamsen; Ove B Schaffalitzky de Muckadell
Publication Detail:
Type:  English Abstract; Journal Article; Review    
Journal Detail:
Title:  Ugeskrift for laeger     Volume:  169     ISSN:  1603-6824     ISO Abbreviation:  Ugeskr. Laeg.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-05-08     Completed Date:  2007-05-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0141730     Medline TA:  Ugeskr Laeger     Country:  Denmark    
Other Details:
Languages:  dan     Pagination:  1551-5     Citation Subset:  IM    
Herlev Hospital, Kirurgisk Gastroenterologisk Afdeling D, Herlev.
Vernacular Title:
Behandling af blødende gastroduodenalt peptisk ulcus.
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MeSH Terms
Antacids / therapeutic use
Antifibrinolytic Agents / therapeutic use
Duodenal Ulcer / diagnosis,  mortality,  therapy*
Embolization, Therapeutic
Epinephrine / therapeutic use
Helicobacter Infections / diagnosis,  drug therapy
Helicobacter pylori
Peptic Ulcer Hemorrhage / diagnosis,  mortality,  therapy*
Proton Pumps / antagonists & inhibitors
Stomach Ulcer / diagnosis,  mortality,  therapy*
Tranexamic Acid / therapeutic use
Vasoconstrictor Agents / therapeutic use
Reg. No./Substance:
0/Antacids; 0/Antifibrinolytic Agents; 0/Proton Pumps; 0/Vasoconstrictor Agents; 1197-18-8/Tranexamic Acid; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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