Document Detail


Treatment adherence in patients with rheumatoid arthritis and systemic lupus erythematosus.
MedLine Citation:
PMID:  18185905     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study assessed self-reported adherence in patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) from underserved healthcare settings. We conducted a cross-sectional survey of 102 ethnically diverse patients--70 with RA and 32 with SLE--attending rheumatology clinics at publicly funded hospitals in Houston, Texas; 43% were Hispanic, 32% African-American, and 25% White. Treatment adherence was evaluated using the compliance questionnaire rheumatology (CQR; 0, low adherence and 100, high adherence) and the questionnaire of the Adult AIDS Clinical Trials Group (AACTG). The patients were also asked how often they forgot to take their prescribed medications or discontinued them on their own. Mean patient age was 48.5 years; 75% were female, 32% were African-American, 43% Hispanic, and 25% White. Only one third reported never forgetting to take their medications; 40% reported having stopped their medications on their own because of side effects, and 20% because of lack of efficacy. Mean CQR score was 69.1 +/- 10.5, suggesting moderate adherence overall. Differences were also observed across ethnic groups: 23% of ethnic minority patients had problems taking their medications at specified times compared to 11% of Whites (p = 0.03). Lower education and side effects were associated with lower adherence. No differences were observed between RA and SLE patients. Many patients with RA and SLE report problems with treatment adherence. These appear to be more prevalent in African Americans and Hispanics than Whites; the impact of decreased adherence on outcomes could be significant and should be considered when treating patients with RA and SLE.
Authors:
Araceli Garcia-Gonzalez; Marsha Richardson; Maria Garcia Popa-Lisseanu; Vanessa Cox; Michael A Kallen; Namieta Janssen; Bernard Ng; Donald M Marcus; John D Reveille; Maria E Suarez-Almazor
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2008-01-08
Journal Detail:
Title:  Clinical rheumatology     Volume:  27     ISSN:  0770-3198     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-06-06     Completed Date:  2008-08-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  883-9     Citation Subset:  IM    
Affiliation:
University of Texas M.D Anderson Cancer Center, Anderson 1400 Holcombe Boulevard Unit 437, Houston, TX 77030, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
African Americans
Aged
Antirheumatic Agents / adverse effects
Arthritis, Rheumatoid / drug therapy*,  ethnology
Cross-Sectional Studies
Educational Status
European Continental Ancestry Group
Female
Hispanic Americans
Humans
Lupus Erythematosus, Systemic / drug therapy*,  ethnology
Male
Medically Underserved Area
Middle Aged
Patient Compliance / ethnology*
Grant Support
ID/Acronym/Agency:
R01 AR47858/AR/NIAMS NIH HHS; U18 HS016093/HS/AHRQ HHS
Chemical
Reg. No./Substance:
0/Antirheumatic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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