| Treatment of acute infectious purpura fulminans with activated protein C. | |
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MedLine Citation:
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PMID: 16820663 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Infectious purpura fulminans is associated with high mortality and morbidity despite standard antimicrobial therapy. We report satisfactory clinical outcome in two children with sepsis associated purpura fulminans who were treated with activated protein C (APC). There is need for proper evaluation of the efficacy of this extremely expensive therapeutic modality by randomized controlled trials before it is made standard of care in childhood infectious purpura fulminans. |
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Authors:
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M R Lokeshwar; T Singhal; S V Udani; F N Kapadia |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Indian pediatrics Volume: 43 ISSN: 0019-6061 ISO Abbreviation: Indian Pediatr Publication Date: 2006 Jun |
Date Detail:
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Created Date: 2006-07-05 Completed Date: 2006-09-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985062R Medline TA: Indian Pediatr Country: India |
Other Details:
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Languages: eng Pagination: 535-8 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, P.D. Hinduja National Hospital and Research Center, Veer Savarkar Marg, Mumbai 400 016, India. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Anticoagulants / therapeutic use* Blood Coagulation Factors / drug effects* Child, Preschool Humans Infant Male Protein C / therapeutic use* Purpura, Schoenlein-Henoch / drug therapy* Receptors, Cell Surface / drug effects* Treatment Outcome* |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 0/Blood Coagulation Factors; 0/Protein C; 0/Receptors, Cell Surface; 0/activated protein C receptor |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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