Document Detail

Treatment of actinic cheilitis with the Er:YAG laser.
MedLine Citation:
PMID:  20846565     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Actinic cheilitis is a common condition with the potential to develop into squamous cell carcinoma. Current treatments have varying cure rates and complications. The role of the erbium:yttrium-aluminum-garnet (Er:YAG) laser in the treatment of actinic cheilitis has not been widely published, despite offering theoretical advantages over current treatment modalities. OBJECTIVE: To evaluate the outcome of a series of patients treated with the Er:YAG laser for actinic cheilitis. METHODS: This was a retrospective, interventional, nonrandomized, sequential case series set in a tertiary referral, dermatologic surgery unit. Ninety-nine consecutive patients with actinic cheilitis treated with the Er:YAG laser between January 2001 and June 2008 underwent a case note review, of which 77 went on to a structured telephone interview. The main outcome measures were a subjective improvement in lip symptoms related to actinic cheilitis and objective improvement in the lips at routine follow-up. RESULTS: Mean time to interview follow-up was 65.7 months. Of those interviewed, 92.2% believed there had been an improvement in the cosmetic appearance of their lips; one hundred percent believed the function of their lips had improved or remained unchanged; and 84.8% remained completely disease free at the time of follow-up. The majority of patients (93.5%) were satisfied with the laser treatment. Scarring as a direct result of the laser occurred in 5.1% of patients. LIMITATIONS: Retrospective nature of data collection; inability to interview all patients who underwent treatment. CONCLUSION: The Er:YAG laser is a successful modality for the treatment of actinic cheilitis with good functional and cosmetic results and only a small risk of long-term scarring. It should be considered as a first-line treatment for the disease.
Paul Armenores; Craig L James; Patrick C Walker; Shyamala C Huilgol
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  63     ISSN:  1097-6787     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-17     Completed Date:  2010-10-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  642-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2009 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.
Flinders Medical Centre, Bedford Park, Adelaide, Australia.
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MeSH Terms
Aged, 80 and over
Carcinoma, Squamous Cell / pathology,  prevention & control
Cheilitis / pathology*,  surgery*
Follow-Up Studies
Intervention Studies
Laser Therapy / methods*
Lasers, Solid-State*
Middle Aged
Precancerous Conditions / pathology,  surgery*
Retrospective Studies
Risk Assessment
Severity of Illness Index
Skin Neoplasms / pathology,  prevention & control
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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