Document Detail

Treatment of acne with 5% benzoyl peroxide gel or 0.05% retinoic acid cream.
MedLine Citation:
PMID:  157264     Owner:  NLM     Status:  MEDLINE    
In a parallel group comparison of a 5% benzoyl peroxide gel with a 0.05% retinoic acid cream, in moderate facial acne vulgaris, significantly more patients in the benzoyl peroxide group experienced overall excellent results than did those in the other group. Both medications, however, were effective in reducing the numbers of both inflammatory and noninflammatory lesions. The benzoyl peroxide gel appeared to produce a more rapid effect on inflammatory lesions than did retinoic acid, and produced significantly less peeling.
B S Belknap
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Cutis     Volume:  23     ISSN:  0011-4162     ISO Abbreviation:  Cutis     Publication Date:  1979 Jun 
Date Detail:
Created Date:  1979-10-24     Completed Date:  1979-10-24     Revised Date:  2013-09-12    
Medline Journal Info:
Nlm Unique ID:  0006440     Medline TA:  Cutis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  856-9     Citation Subset:  IM    
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MeSH Terms
Acne Vulgaris / drug therapy*
Administration, Topical
Benzoyl Peroxide / administration & dosage,  therapeutic use*
Clinical Trials as Topic
Peroxides / therapeutic use*
Time Factors
Tretinoin / administration & dosage,  therapeutic use*
Vitamin A / analogs & derivatives*
Reg. No./Substance:
0/Peroxides; 11103-57-4/Vitamin A; 302-79-4/Tretinoin; 94-36-0/Benzoyl Peroxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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