| A treatment trial of vitamin D supplementation in breast-fed infants: Universal supplementation is not necessary for rickets prevention in Southern Louisiana. | |
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MedLine Citation:
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PMID: 20724336 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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This study was conducted to determine if vitamin D supplementation is required to prevent rickets in breast-fed infants. Breast-feeding rates are increasing, and there are concerns about whether the vitamin D content of breast milk is sufficient. There are a few treatment trials of vitamin D supplementation in breast-fed infants; these were conducted in northern climates. The authors therefore performed a prospective clinical trial comparing vitamin D supplementation with placebo as control in southern Louisiana. Blood samples and questionnaires were collected at birth, 2, 4, and 6 months of age. There were no cases of rickets observed, and no differences in alkaline phosphatase levels between groups. Thus, there was no evidence that vitamin D supplementation reduced rickets risk in the authors' study population. This suggests that the current recommendations for universal vitamin D supplementation of breast-fed infants throughout the United States may need to be revised. |
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Authors:
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Tulasi Ponnapakkam; Elease Bradford; Robert Gensure |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-08-19 |
Journal Detail:
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Title: Clinical pediatrics Volume: 49 ISSN: 1938-2707 ISO Abbreviation: Clin Pediatr (Phila) Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372606 Medline TA: Clin Pediatr (Phila) Country: United States |
Other Details:
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Languages: eng Pagination: 1053-60 Citation Subset: AIM; IM |
Affiliation:
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Ochsner Clinic Foundation, New Orleans, LA 70121, USA. tponnapakkam@ochsner.org |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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