| Treatment and Screening of Hypothyroidism in Pregnancy: Results of a European Survey. | |
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MedLine Citation:
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PMID: 22023792 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background: Maternal hypothyroidism in pregnancy is associated with several adverse outcomes. The Endocrine Society guidelines for the management of thyroid diseases in pregnancy were published in 2007; however, impact of the guidelines in the routine clinical practice is unknown. Therefore, we have carried out a survey of members of the European Thyroid Association to study current practices relating to the management of hypothyroidism in pregnancy.Subjects and methods: In December 2010, we emailed an electronic questionnaire survey based on clinical case scenarios to 605 members of the ETA. Responses from 190 clinician members (from 28 European countries) were analysed.Results: For a pregnant woman with newly diagnosed overt hypothyroidism, most responders initiated a full dose of L-thyroxine. For a woman with hypothyroidism planning pregnancy, 50% recommended increasing the dose of L-thyroxine as soon as pregnancy is confirmed, whilst 43% favoured testing thyroid function before adjusting the dose. Responders used diverse combinations of tests to monitor the dose of L-thyroxine. The target of thyroid function tests that responders aimed to achieve with L-thyroxine was also inconsistent. Forty-two percent responders or their institutions screened all pregnant women for thyroid dysfunction, 43% performed targeted screening of only the high-risk group, whilst 17% did not carry out systemic screening. Timing of the screening, tests used, and criteria for starting treatment and monitoring were variable.Conclusions: There is wide variation in the clinical practice relating to the treatment and screening of hypothyroidism during pregnancy in Europe. |
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Authors:
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Bijay Vaidya; Alicja Hubalewska-Dydejczyk; Peter Laurberg; Roberto Negro; Francesco Vermiglio; Kris Gustave Poppe |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-24 |
Journal Detail:
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Title: European journal of endocrinology / European Federation of Endocrine Societies Volume: - ISSN: 1479-683X ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9423848 Medline TA: Eur J Endocrinol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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B Vaidya, Department of Endocrinology, Peninsula Medical School, Exeter, EX2 5DW, United Kingdom. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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