Document Detail

Treatment of Peyronie's disease by extracorporeal shockwave therapy: evaluation of our preliminary results.
MedLine Citation:
PMID:  10597123     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Peyronie's disease is an idiopathic disorder of the penis that produces erectile dysfunction. It affects mainly the tunica albuginea. We describe our preliminary results with extracorporal shockwave therapy (ESWT) as a new noninvasive modality for the treatment of Peyronie's disease. PATIENTS AND METHODS: In this study, 24 patients aged 36 to 67 years were treated with ESWT on the Lithostar overhead-module (Siemens). All our patients had unsuccessful medical treatment before ESWT. The average plaque was 7x15 mm. The number of shockwaves ranged from 15,000 to 25,000 (18-21 kV) delivered in four to ten sessions. Most patients needed local anesthesia before therapy. RESULTS: Four patients (17%) showed marked improvement and complete remission of the penile deviation. Six patients (25%) showed partial remission with painless erections after treatment. Four patients had painless erections after treatment but still had some penile deviation. In 10 patients (41%), ESWT failed, necessitating subsequent penile surgery. CONCLUSIONS: Our preliminary results with a response rate of 59% with ESWT for Peyronie's disease, including a 17% complete remission rate, is encouraging. However, further multicenter studies will have to prove if ESWT is a real therapeutic option for this disease.
Y Abdel-Salam; Z Budair; C Renner; T Frede; J Rassweiler; F El-Annany; H El-Magraby; M El-Akkad
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of endourology / Endourological Society     Volume:  13     ISSN:  0892-7790     ISO Abbreviation:  J. Endourol.     Publication Date:  1999 Oct 
Date Detail:
Created Date:  2000-01-07     Completed Date:  2000-01-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8807503     Medline TA:  J Endourol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  549-52     Citation Subset:  IM    
Urology Department, Klinikum Heilbronn, University at Heidelberg, Germany.
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MeSH Terms
Equipment Design
Erectile Dysfunction / etiology,  therapy,  ultrasonography
Lithotripsy / instrumentation*
Middle Aged
Penile Induration / complications,  therapy*,  ultrasonography
Penis / ultrasonography
Retrospective Studies
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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