Document Detail


Treatment of obese adolescents: the influence of periodization models and ACE genotype.
MedLine Citation:
PMID:  19680237     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aims of the present study were to compare the effects of two periodization models on metabolic syndrome risk factors in obese adolescents and verify whether the angiotensin-converting enzyme (ACE) genotype is important in establishing these effects. A total of 32 postpuberty obese adolescents were submitted to aerobic training (AT) and resistance training (RT) for 14 weeks. The subjects were divided into linear periodization (LP, n = 16) or daily undulating periodization (DUP, n = 16). Body composition, visceral and subcutaneous fat, glycemia, insulinemia, homeostasis model assessment of insulin resistance (HOMA-IR), lipid profiles, blood pressure, maximal oxygen consumption (VO(2max)), resting metabolic rate (RMR), muscular endurance were analyzed at baseline and after intervention. Both groups demonstrated a significant reduction in body mass, BMI, body fat, visceral and subcutaneous fat, total and low-density lipoprotein cholesterol, blood pressure and an increase in fat-free mass, VO(2max), and muscular endurance. However, only DUP promoted a reduction in insulin concentrations and HOMA-IR. It is important to emphasize that there was no statics difference between LP and DUP groups; however, it appears that there may be bigger changes in the DUP than LP group in some of the metabolic syndrome risk factors in obese adolescents with regard to the effect size (ES). Both periodization models presented a large effect on muscular endurance. Despite the limitation of sample size, our results suggested that the ACE genotype may influence the functional and metabolic characteristics of obese adolescents and may be considered in the future strategies for massive obesity control.
Authors:
Denis Foschini; Ronaldo C Araújo; Reury F P Bacurau; Aline De Piano; Sandro S De Almeida; June Carnier; Thiago D S Rosa; Marco T De Mello; Sérgio Tufik; Ana R Dâmaso
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-08-13
Journal Detail:
Title:  Obesity (Silver Spring, Md.)     Volume:  18     ISSN:  1930-739X     ISO Abbreviation:  Obesity (Silver Spring)     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-29     Completed Date:  2010-09-02     Revised Date:  2012-08-13    
Medline Journal Info:
Nlm Unique ID:  101264860     Medline TA:  Obesity (Silver Spring)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  766-72     Citation Subset:  IM    
Affiliation:
Post Graduate Program of Nutrition, Federal University of São Paulo, Paulista Medicine School, UNIFESP-EPM, São Paulo, Brazil. denisfoschini@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Blood Pressure
Body Composition
Body Mass Index
Body Weight
Cholesterol / blood
Exercise / physiology*
Female
Genetic Predisposition to Disease
Genotype
Humans
Insulin / blood*
Insulin Resistance / genetics
Male
Metabolic Syndrome X / blood,  genetics,  prevention & control*
Models, Biological*
Muscle Strength / physiology
Obesity / blood,  genetics,  therapy*
Oxygen Consumption
Peptidyl-Dipeptidase A / genetics*
Physical Endurance
Resistance Training / methods*
Risk Factors
Chemical
Reg. No./Substance:
0/Insulin; 57-88-5/Cholesterol; EC 3.4.15.1/Peptidyl-Dipeptidase A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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