Document Detail


Treatment of Kounis syndrome.
MedLine Citation:
PMID:  20206392     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Kounis syndrome is potentially a life-threatening medical emergency with both a severe allergic reaction and acute coronary syndrome. Most of the information about this syndrome has come from the case reports. The management of these patients may be challenging for clinicians, and unfortunately guidelines have not been established yet. In this article, we review the current guidelines of acute coronary syndromes and anaphylaxis along with the published cases with Kounis syndrome secondary to beta-lactam antibiotics. We have summarized our recommendations for the work-up and treatment of Kounis syndrome from available data. Obviously, larger prospective studies are needed to establish definitive treatment guidelines for these patients.
Authors:
Cihan Cevik; Kenneth Nugent; Goutam P Shome; Nicholas G Kounis
Publication Detail:
Type:  Journal Article; Review     Date:  2010-03-04
Journal Detail:
Title:  International journal of cardiology     Volume:  143     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-13     Completed Date:  2010-12-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  223-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Texas Tech University Health Sciences Center, Department of Internal Medicine, Lubbock, TX 79430, United States. cihan.cevik@ttuhsc.edu
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MeSH Terms
Descriptor/Qualifier:
Acute Coronary Syndrome / drug therapy*,  etiology
Anaphylaxis / drug therapy*,  etiology
Cardiovascular Agents / therapeutic use*
Drug Hypersensitivity*
Epinephrine / therapeutic use
Histamine Antagonists / therapeutic use*
Humans
Immunosuppressive Agents / therapeutic use
Practice Guidelines as Topic
Chemical
Reg. No./Substance:
0/Cardiovascular Agents; 0/Histamine Antagonists; 0/Immunosuppressive Agents; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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