Document Detail


Treatment of Guillain-Barré syndrome induced by cyclosporine in a lung transplant patient.
MedLine Citation:
PMID:  16399546     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the case of a 58-year-old man with severe chronic obstructive pulmonary disease who developed acute quadriparesis during the post-operative period following bilateral lung transplantation after receiving cyclosporine for immunosuppression. Electromyography with nerve conduction study and cerebrospinal fluid analysis supported a diagnosis of Guillain-Barré Syndrome, which improved upon the discontinuation of cyclosporine, replacement with tacrolimus, and initiation of plasmapheresis. We propose the discontinuation of cyclosporine and initiation of plasmapheresis as a treatment for cyclosporine-associated Guillain-Barré syndrome.
Authors:
Jeremy A Falk; Francis C Cordova; Anca Popescu; Gabriel Tatarian; Gerard J Criner
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2005-11-14
Journal Detail:
Title:  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation     Volume:  25     ISSN:  1557-3117     ISO Abbreviation:  J. Heart Lung Transplant.     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-01-09     Completed Date:  2006-06-23     Revised Date:  2006-12-19    
Medline Journal Info:
Nlm Unique ID:  9102703     Medline TA:  J Heart Lung Transplant     Country:  United States    
Other Details:
Languages:  eng     Pagination:  140-3     Citation Subset:  IM    
Affiliation:
Division of Pulmonary and Critical Care Medicine, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA. jfalk@usc.edu
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MeSH Terms
Descriptor/Qualifier:
Cyclosporine / adverse effects*,  therapeutic use
Guillain-Barre Syndrome / therapy*
Humans
Immunosuppressive Agents / adverse effects*,  therapeutic use
Lung Transplantation*
Male
Middle Aged
Plasmapheresis*
Pulmonary Disease, Chronic Obstructive / surgery
Treatment Outcome
Chemical
Reg. No./Substance:
0/Immunosuppressive Agents; 59865-13-3/Cyclosporine
Comments/Corrections
Comment In:
J Heart Lung Transplant. 2006 Nov;25(11):1387   [PMID:  17097509 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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