Document Detail

Treatment of CO2 laser induced hypopigmentation with ablative fractionated laser resurfacing: case report and review of the literature.
MedLine Citation:
PMID:  21061766     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The carbon dioxide laser (CO2) has been proven to be an effective device for the treatment of photoaging. However, it is associated with adverse side effects including prolonged erythema, edema, burning, milia, acne, crusting and hypo-/hyperpigmentation. Delayed onset hypopigmentation after CO, laser resurfacing can markedly detract from clinical outcomes. To overcome the disadvantages of traditional ablative and non-ablative resurfacing, fractional photothermolysis (FP) has been introduced. FP has been demonstrated in early case reports and case series to produce significant improvement in hypopigmentation of acne and surgical scars.
CASE REPORT: A 53-year-old Caucasian female with Fitzpatrick type I skin presented with a nine-month history of delayed onset hypopigmentation following ablative CO2 laser resurfacing. After a series of three treatments at eight-week intervals with an ablative fractionated CO2 laser device, the hypopigmentation and line of pigmentary demarcation between the face and neck improved by 75 percent.
CONCLUSION: Ablative fractional resurfacing is a safe and potentially effective modality for the treatment of CO2 laser induced hypopigmentation on the face.
Emily P Tierney; C William Hanke
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of drugs in dermatology : JDD     Volume:  9     ISSN:  1545-9616     ISO Abbreviation:  J Drugs Dermatol     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-10     Completed Date:  2010-12-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101160020     Medline TA:  J Drugs Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1420-6     Citation Subset:  IM    
Tufts University School of Medicine, Boston, MA 02111, USA.
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MeSH Terms
Hypopigmentation / etiology*,  surgery*
Laser Therapy / adverse effects*
Lasers, Gas / adverse effects*
Middle Aged
Skin Aging

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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