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Treatment of bilateral hand frostbite using transcatheter arterial thrombolysis after papaverine infusion.
MedLine Citation:
PMID:  19449067     Owner:  NLM     Status:  In-Process    
Standard therapy for frostbite has been unaltered for more than 20 years. Recently there have been reports of improved outcomes with the addition of a vasodilator to intra-arterial thrombolytic therapy. We report the case of severe frostbite of the hands successfully treated with transcatheter intra-arterial tPA after papaverine infusion in a 37-year-old man. Upper extremity and hand angiography within 16 h of the insult showed thrombotic occlusive disease and vasospasm. Intra-arterial catheters were placed in the brachial arteries and a papaverine infusion was initiated, followed by intra-arterial tPA thrombolysis. Follow-up examination at 4 months revealed full hand function and complete resolution of symptoms.
Arash M Saemi; Jason M Johnson; Christopher S Morris
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Publication Detail:
Type:  Journal Article     Date:  2009-05-16
Journal Detail:
Title:  Cardiovascular and interventional radiology     Volume:  32     ISSN:  1432-086X     ISO Abbreviation:  Cardiovasc Intervent Radiol     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-11-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003538     Medline TA:  Cardiovasc Intervent Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1280-3     Citation Subset:  IM    
Section of Interventional Radiology, Department of Radiology, University of Vermont College of Medicine and Fletcher Allen Health Care, Burlington, VT 05401, USA.
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