Document Detail

Treating renal cell cancer in the elderly.
MedLine Citation:
PMID:  16536757     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine whether age and comorbidity are predictors of peri-operative complications and/or mortality in surgery for renal cell cancer in a retrospective study of patients aged >75 years. PATIENTS AND METHODS: Between 1993 and 2003, 1023 radical nephrectomies or nephron-sparing surgery for renal cell cancer were performed in 115 consecutive patients aged > or = 75 years and in 908 consecutive patients aged <75 years. The preoperative American Society of Anesthesiologists (ASA) score was used for risk stratification. Operative mortality and early complications (within 30 days of surgery) were reviewed. RESULTS: The younger patients had significantly lower ASA scores than the older patients. There were early complications in 31 of the 908 younger patients (3.4%) and in two of the 115 older patients (1.7%). Peri-operative mortality was higher in the older than in the younger patients (1.7% vs 0.3%; P = 0.29). Overall morbidity and mortality correlated with increasing ASA score but not with age (P < 0.05). CONCLUSIONS: Despite greater comorbidity in older patients, their morbidity and mortality did not differ significantly from that of younger patients. Advanced age alone should thus not be used as a criterion to deny surgery for renal cell carcinoma. However, older patients should be counselled regarding a tendency for increased comorbidity-related peri-operative mortality.
Navid Berdjis; Oliver W Hakenberg; Vladimir Novotny; Michael Froehner; Manfred P Wirth
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  BJU international     Volume:  97     ISSN:  1464-4096     ISO Abbreviation:  BJU Int.     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-03-15     Completed Date:  2006-04-24     Revised Date:  2006-07-18    
Medline Journal Info:
Nlm Unique ID:  100886721     Medline TA:  BJU Int     Country:  England    
Other Details:
Languages:  eng     Pagination:  703-5     Citation Subset:  IM    
Department of Urology, University Hospital Carl Gustav Carus, Technical University Dresden, Fetscherstrasse 74, D-01309 Dresden, Germany.
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MeSH Terms
Age Factors
Aged, 80 and over
Carcinoma, Renal Cell / mortality,  surgery*
Kidney Neoplasms / mortality,  surgery*
Middle Aged
Nephrectomy / methods*,  mortality
Retrospective Studies
Risk Factors
Treatment Outcome

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