| Treating high blood pressure: is reaching the target more important than the means? No, the means are important. | |
| | |
MedLine Citation:
|
PMID: 21111930 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
All major antihypertensive drug classes i.e. diuretics, beta-blockers, calcium antagonists and blockers of the renin-angiotensin system have been shown to effectively lower blood pressure and hence to reduce cardiovascular outcomes in hypertensive patients. These drugs decrease cardiovascular complications in hypertension essentially because they reduce systemic blood pressure. Nevertheless, there is growing evidence that the extent of the benefits differed between drug classes suggesting that the various classes of antihypertensive agents are not equivalent in their ability to protect against target organ damages and cardiovascular and renal endpoints. More recently, evidence has also accumulated to demonstrate that even combination therapies are not equally effective in reducing the occurrence of cardiovascular complications in hypertension. These recent observations suggest that the means to lower blood pressure are as important as the achieved target blood pressure in the management of hypertensive patients. |
| | |
Authors:
|
Valentina Forni; Grégoire Wuerzner; Menno Pruijm; Michel Burnier |
Publication Detail:
|
Type: Journal Article Date: 2010-09-17 |
Journal Detail:
|
Title: European journal of internal medicine Volume: 21 ISSN: 1879-0828 ISO Abbreviation: Eur. J. Intern. Med. Publication Date: 2010 Dec |
Date Detail:
|
Created Date: 2010-11-29 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9003220 Medline TA: Eur J Intern Med Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 478-83 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 European Federation of Internal Medicne. Published by Elsevier B.V. All rights reserved. |
Affiliation:
|
Service of Nephrology and Hypertension, Department of Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Treating high blood pressure: is reaching the target more important than the means? Yes, the target ...
Next Document: Inhibition of the antithrombotic effects of clopidogrel by proton pump inhibitors: facts or fancies?