| Treating delayed endoscopic sphincterotomy-induced bleeding: epinephrine injection with or without thermotherapy. | |
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MedLine Citation:
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PMID: 19824118 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To compare the hemostatic efficacy between epinephrine injection alone and epinephrine injection combined with thermotherapy for delayed post-endoscopic sphincterotomy (ES) bleeding. METHODS: Cases with delayed post-ES bleeding undergoing epinephrine injection alone (epinephrine injection group, n = 26) or epinephrine combined with thermotherapy (combination therapy group, n = 33) in our institution between 1999 and 2007 were retrospectively investigated. The main outcome measurements were: initial endoscopic hemostasis, re-bleeding, complications, requirement of angiographic embolization or surgery, requirement for blood transfusion, and mortality. RESULTS: The initial hemostatic efficacy was 96.2% for epinephrine injection alone and 100% for combination therapy (P = 0.44). There were four patients with re-bleeding in each group (16.0% vs 12.1%, P = 0.72). There was only one complication of pancreatitis from the combination therapy group. Three patients (11.5%) in the epinephrine injection group and one patient (3%) in the combination therapy group required angiographic embolization or surgery (P = 0.31). The total number of blood transfusions was not significantly different between the two groups (3.5 +/- 4.6 U vs 3.5 +/- 4.5 U, P = 0.94). There was no bleeding-related death in either group. CONCLUSION: Epinephrine injection alone is as effective as epinephrine injection combined with thermotherapy for the management of delayed post-ES bleeding. |
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Authors:
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Yung-Kuan Tsou; Cheng-Hui Lin; Nai-Jen Liu; Jui-Hsiang Tang; Kai-Feng Sung; Chi-Liang Cheng; Ching-Song Lee |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: World journal of gastroenterology : WJG Volume: 15 ISSN: 1007-9327 ISO Abbreviation: World J. Gastroenterol. Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-10-13 Completed Date: 2010-01-27 Revised Date: 2010-09-27 |
Medline Journal Info:
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Nlm Unique ID: 100883448 Medline TA: World J Gastroenterol Country: China |
Other Details:
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Languages: eng Pagination: 4823-8 Citation Subset: IM |
Affiliation:
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Department of Hepato-Gastroenterology, Division of Therapeutic Endoscopy, Chang Gung Memorial Hospital & Chang Gung University College of Medicine, Taipei, Taiwan, ROC. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Cholangiopancreatography, Endoscopic Retrograde / methods* Endoscopy / methods Epinephrine / pharmacology* Female Hemorrhage Hemostasis Humans Hyperthermia, Induced / methods* Male Middle Aged Retrospective Studies Sphincterotomy, Endoscopic / adverse effects* Treatment Outcome Vasoconstrictor Agents / pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Vasoconstrictor Agents; 51-43-4/Epinephrine |
| Comments/Corrections | |
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