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Treating chronic fatigue syndrome - a study into the scientific evidence for pharmacological treatments.
MedLine Citation:
PMID:  22059223     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Background Chronic fatigue syndrome, or myalgic encephalomyelitis (CFS), is a severe disabling condition. Patients with CFS usually trial many different medicines, both conventional and complementary. An overview of the pharmacological treatments used by CFS patients and the available evidence underpinning the use of these treatments would be of great value to both patients and their healthcare providers. Methods Ninety-four CFS patients recruited into an Australian study investigating immunological biomarkers filled out a questionnaire assessing the medicines they were taking. Evidence from randomised clinical trials was sought in biomedical databases. Results The 94 CFS patients used 474 different medicines and supplements. The most commonly used medicines were antidepressants, analgesics, sedatives, and B vitamins. We identified 20 randomised controlled trials studying these medicines in CFS patients. Discussion While conventional and complementary medicines are widely used by CFS patients, the evidence for effectiveness in CFS is very limited.
Authors:
Sanne Kreijkamp-Kaspers; Ekua Weba Brenu; Sonya Marshall; Don Staines; Mieke L Van Driel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Australian family physician     Volume:  40     ISSN:  0300-8495     ISO Abbreviation:  Aust Fam Physician     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0326701     Medline TA:  Aust Fam Physician     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  907-12     Citation Subset:  IM    
Affiliation:
MD, PhD, FRACGP, MSc, is Assistant Professor, Academic General Practice, Faculty of Health Sciences & Medicine, Bond University, Gold Coast, Queensland.
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