Document Detail

Treating acute acetaminophen poisoning with acetylcysteine.
MedLine Citation:
PMID:  576943     Owner:  NLM     Status:  MEDLINE    
A patient ingested 15.6 gm acetaminophen and sought medical attention after seven hours. At that time, her plasma acetaminophen level was 217 microng/ml. Treatment with acetylcysteine was begun eight hours after the ingestion. The clinical course of this patient was characterized by a mild illness with a minor elevation of liver enzyme values. A number of factors predicted severe hepatotoxicity for this patient had she not received treatment.
R G Peterson; B H Rumack
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  JAMA     Volume:  237     ISSN:  0098-7484     ISO Abbreviation:  JAMA     Publication Date:  1977 May 
Date Detail:
Created Date:  1977-06-30     Completed Date:  1977-06-30     Revised Date:  2014-09-17    
Medline Journal Info:
Nlm Unique ID:  7501160     Medline TA:  JAMA     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2406-7     Citation Subset:  AIM; IM    
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MeSH Terms
Acetaminophen / administration & dosage,  antagonists & inhibitors,  poisoning*
Acetylcysteine / pharmacology,  therapeutic use*
Acute Disease
Liver / drug effects
Middle Aged
Suicide, Attempted
Reg. No./Substance:
362O9ITL9D/Acetaminophen; WYQ7N0BPYC/Acetylcysteine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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