Document Detail

Traveler's diarrhea.
MedLine Citation:
PMID:  15952437     Owner:  NLM     Status:  MEDLINE    
Acute diarrhea affects millions of persons who travel to developing countries each year. Food and water contaminated with fecal matter are the main sources of infection. Bacteria such as enterotoxigenic Escherichia coli, enteroaggregative E. coli, Campylobacter, Salmonella, and Shigella are common causes of traveler's diarrhea. Parasites and viruses are less common etiologies. Travel destination is the most significant risk factor for traveler's diarrhea. The efficacy of pretravel counseling and dietary precautions in reducing the incidence of diarrhea is unproven. Empiric treatment of traveler's diarrhea with antibiotics and loperamide is effective and often limits symptoms to one day. Rifaximin, a recently approved antibiotic, can be used for the treatment of traveler's diarrhea in regions where noninvasive E. coli is the predominant pathogen. In areas where invasive organisms such as Campylobacter and Shigella are common, fluoroquinolones remain the drug of choice. Azithromycin is recommended in areas with quinolone-resistant Campylobacter and for the treatment of children and pregnant women.
Johnnie Yates
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  American family physician     Volume:  71     ISSN:  0002-838X     ISO Abbreviation:  Am Fam Physician     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-06-14     Completed Date:  2005-07-14     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  1272646     Medline TA:  Am Fam Physician     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2095-100     Citation Subset:  AIM; IM    
CIWEC Clinic Travel Medicine Center, Kathmandu, Nepal.
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MeSH Terms
Acute Disease
Anti-Bacterial Agents / therapeutic use
Antibiotic Prophylaxis
Diarrhea* / complications,  microbiology,  prevention & control
Risk Factors
Reg. No./Substance:
0/Anti-Bacterial Agents

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