Document Detail


Transvenous cardioverter defibrillator lead malfunction due to terminal connector damage in pectoral implants.
MedLine Citation:
PMID:  10642134     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lead failure places patients with implantable cardioverter defibrillators (ICD) at risk for sudden cardiac death or results in delivery of inappropriate shocks. This study describes a mechanism of lead malfunction occurring at the junction of the terminal ring with the conductor coil of the rate sensing terminal connector in one specific model of a transvenous ICD lead. We detected the problem in a population of 179 patients with a mean age of 61 +/- 10 years and a mean lead implant duration of 16 +/- 11 months. All patients underwent pectoral ICD implantation using a submuscular approach. The implanting physician chose to place the ICD on the left side in 155 patients (87%) and on the right side in 24 patients (13%). Cephalic vein cutdown provided central venous access in 147 patients (82%), and subclavian vein puncture provided access in 32 patients (18%). Follow-up examination detected lead failure in six patients (3.5% over 31 months) due to insulation damage with or without conductor coil fracture at the junction of the terminal ring and conductor coil of the IS-1 rate sense terminal. We detected lead disruption 17 +/- 9 months (range 5-31 months) after implantation. Multiple nonsustained arrhythmia episodes exhibiting nonphysiologic intervals associated with noisy rate sensing electrograms during pocket manipulation led to discovery in three patients. The other three patients presented with inappropriate device discharges confirmed by stored high-energy lead electrograms showing normal rhythm. Pacing lead impedance abnormally dropped in two patients. Impedance remained stable in the other four patients. In conclusion, the generator pocket represents an important site of ICD transvenous lead vulnerability. Lead failure may result from conductor coil and/or insulation disruption at the interface with the rate sensing terminal connector.
Authors:
F Mera; D B DeLurgio; J J Langberg; E A Moss; A R Léon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  22     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  1999 Dec 
Date Detail:
Created Date:  2000-02-03     Completed Date:  2000-02-03     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1797-801     Citation Subset:  IM    
Affiliation:
Carlyle Fraser Heart Center at Crawford Long Hospital, Emory University School of Medicine, Atlanta, Georgia 30365, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Arm / blood supply
Arrhythmias, Cardiac / diagnosis
Artifacts
Axillary Vein
Catheterization, Central Venous / instrumentation
Death, Sudden, Cardiac / etiology
Defibrillators, Implantable* / adverse effects
Electric Countershock / adverse effects
Electric Impedance
Electrocardiography
Equipment Failure
Female
Follow-Up Studies
Humans
Male
Middle Aged
Pectoralis Muscles / surgery
Risk Factors
Subclavian Vein
Surface Properties
Venous Cutdown

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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