| Transvaginal sonographic cervical length for the prediction of spontaneous preterm birth in twin pregnancies: a systematic review and metaanalysis. | |
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MedLine Citation:
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PMID: 20576253 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To assess the accuracy of transvaginal sonographic cervical length (CL) in predicting spontaneous preterm birth in women with twin pregnancies. STUDY DESIGN: Systematic review and metaanalysis of predictive test accuracy. RESULTS: Twenty-one studies (16 in asymptomatic women and 5 in symptomatic women) with a total of 3523 women met the inclusion criteria. Among asymptomatic women, a CL <or=20 mm at 20-24 weeks' gestation was the most accurate in predicting preterm birth <32 and <34 weeks' gestation (pooled sensitivities, specificities, and positive and negative likelihood ratios of 39% and 29%, 96% and 97%, 10.1 and 9.0, and 0.64 and 0.74, respectively). A CL <or=25 mm at 20-24 weeks' gestation had a pooled positive likelihood ratio of 9.6 to predict preterm birth <28 weeks' gestation. The predictive accuracy of CL for preterm birth was low in symptomatic women. CONCLUSION: Transvaginal sonographic CL at 20-24 weeks' gestation is a good predictor of spontaneous preterm birth in asymptomatic women with twin pregnancies. |
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Authors:
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Agustín Conde-Agudelo; Roberto Romero; Sonia S Hassan; Lami Yeo |
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Publication Detail:
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Type: Journal Article; Meta-Analysis; Research Support, N.I.H., Intramural; Review Date: 2010-06-23 |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 203 ISSN: 1097-6868 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-27 Completed Date: 2010-08-17 Revised Date: 2011-08-03 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 128.e1-12 Citation Subset: AIM; IM |
Copyright Information:
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Copyright (c) 2010. Published by Mosby, Inc. |
Affiliation:
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Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development/National Institutes of Health/Department of Health and Human Services, Bethesda, MD, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cervix Uteri
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anatomy & histology,
ultrasonography* Female Gestational Age Humans Incidence Infant, Newborn Predictive Value of Tests Pregnancy Pregnancy Outcome Pregnancy, Multiple* Premature Birth / epidemiology, ultrasonography* Risk Assessment Twins Ultrasonography, Prenatal* |
| Comments/Corrections | |
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