Document Detail

Transvaginal Doppler sonography for evaluation of irregular uterine bleeding with DMPA.
MedLine Citation:
PMID:  20582427     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: The main cause for discontinuation of depot medroxyprogesterone acetate (DMPA) use is irregular menstrual bleeding. The exact pathophysiological mechanisms of irregular bleeding have remained unclear. Transvaginal Doppler is a non-invasive method for studying changes in blood flow which may highlight the underlying pathology in those cases with irregular uterine bleeding. The aim of this study was to quantify the uterine and subendometrial microvasculature in DMPA users with irregular bleeding pattern in comparison to DMPA users with amenorrhea.
STUDY DESIGN: This is a case control study. Forty users of DMPA were divided into two groups: one group included 20 users with irregular uterine bleeding and the second group included 20 amenorrheic users. Pulsatility index (PI) and resistance index (RI) of uterine and subendometrial blood vessels were determined. Power Doppler Energy was used to quantify the signal percentage of the subendometrial area.
RESULTS: There is significant reduction of PI and RI in the uterine artery and subendometrial microvasculature in cases of irregular uterine bleeding.
CONCLUSION: Irregular uterine bleeding with DMPA associated with increased perfusion of uterine and subendometrial blood vessels.
Mostafa Hussein
Related Documents :
3735247 - Direct venous-arterial transfer of 125i-radiolabelled relaxin and tyrosine in the ovari...
17583237 - Ultrasonography in polycystic ovary syndrome: an update.
3710977 - Thermoregulatory and acute-phase responses to endotoxin of full- term-pregnant rabbits.
7928767 - Cell types and hormonal mechanisms associated with mid-cycle corpus luteum function.
11262987 - Oxygen therapy in pediatrics.
24951077 - Transitional hemodynamics in preterm infants with a respiratory management strategy dir...
Publication Detail:
Type:  Journal Article     Date:  2010-06-26
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  283     ISSN:  1432-0711     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1325-8     Citation Subset:  IM    
Obstetrics and Gynecology Department, Woman's Health Center, Assiut University Hospitals, Assiut, Egypt,
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The prognostic significance of optimal debulking in the setting of a complete clinical response for ...
Next Document:  Breast abscess following nipple piercing: a case report and review of the literature.