Document Detail


Transurethral microwave thermotherapy.
MedLine Citation:
PMID:  9933806     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES AND METHODS: The present status of transurethral microwave thermotherapy (TUMT) in the low (LE) and high energy (HE) version is given as an overview. RESULTS: With LE software, approximately 75% of patients will note significant improvement with 65% reduction in symptom scores and a 35-40% improvement in peak flow rate. Sham studies have shown statistically significant improvement in treated patients compared to sham. Randomized studies between TUMT and TURP show similar improvements in symptom scores with TURP producing higher flow rates, as expected. Long-term studies have been reported to 5 years showing durability, although 10-20% of patients subsequently undergo TURP. The clinical efficacy of HE-TUMT 2.5 has been documented in recently completed studies. Approximately 37% of patients develop cavitation with HE-TUMT. The symptomatic improvement is similar between low and high energy while the flow rates with high energy improve by approximately 65%. Pressure flow studies have documented relief of obstruction in most of those patients who had obstruction prior to treatment. The morbidity of HE-TUMT in terms of retrograde ejaculation and posttreatment retention is higher compared to the LE version. CONCLUSIONS: TUMT is a 1-hour out-patient, local anesthetic procedure, minimally invasive treatment option for benign prostatic hyperplasia that encompasses microwave radiative heating and water conductive cooling. TUMT has been proven both safe and efficacious for relieving benign prostatic hyperplasia symptoms in several large-scale controlled studies. The existence of low and high energy versions offers the opportunity to select patients according to obstruction grade.
Authors:
J H Lynch; K Höfner
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  European urology     Volume:  35     ISSN:  0302-2838     ISO Abbreviation:  Eur. Urol.     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-04-15     Completed Date:  1999-04-15     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7512719     Medline TA:  Eur Urol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  129-37     Citation Subset:  IM    
Affiliation:
Department of Surgery, Division of Urology, Georgetown University Medical Center, Washington, DC 20007, USA. lynchj@gunet.georgetown.edu
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MeSH Terms
Descriptor/Qualifier:
Diathermy / instrumentation,  methods*
Humans
Male
Microwaves / therapeutic use*
Patient Selection
Prostatic Hyperplasia / physiopathology,  therapy*
Urodynamics

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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