| Transurethral ethanol injection therapy for prostatic hyperplasia: 3-year results. | |
| | |
MedLine Citation:
|
PMID: 15311027 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: We assessed the medium-term (3-year) efficacy of transurethral ethanol injection therapy of the prostate (EIP) for benign prostatic hyperplasia. MATERIALS AND METHODS: A total of 34 patients were followed for a median of 4.3 years after EIP. Mean age was 68.1 years and mean baseline prostate volume was 49.3 ml. With the patient under combined sacral and urethral anesthesia, dehydrated ethanol was injected into the prostate with endoscopic guidance. A urethral catheter was inserted postoperatively. RESULTS: Mean total ethanol dose was 6.4 ml and a catheter was required for a mean of 7.6 days postoperatively. Mean International Prostate Symptom Score was 21.8 points before EIP (in 34 patients), and decreased to 13.1 points after 3 years (in 17, p <0.01). Mean quality of life index decreased from 5.0 points before EIP to 2.8 points after 3 years (p <0.001). Mean peak urine flow rate was 8.3 ml per second before EIP and increased to 12.7 ml per second after 3 years (p <0.01). Mean residual urine volume decreased from 93 ml before EIP to 28 ml after 3 years (p <0.01). Mean prostate volume decreased from 49.3 ml before EIP to 45.7 ml after 1 year (p <0.001), but increased to 51.4 ml after 3 years. No major complications were experienced. By 3 years after surgery 59.0% of patients had not required further treatment. CONCLUSIONS: Transurethral EIP caused minimal complications while maintaining improvement of the prostate symptom score and an increased peak urine flow after 3 years. |
| | |
Authors:
|
Nobuyuki Goya; Nobuo Ishikawa; Fumio Ito; Chika Kobayashi; Yasuko Tomizawa; Hiroshi Toma |
Related Documents
:
|
15225397 - Plasma kinetic vaporization of the prostate: clinical evaluation of a new technique. 16985897 - Advances in the management of post-radical prostatectomy erectile dysfunction: treatmen... 11455087 - Clinical assessment of sildenafil in the treatment of neurogenic male sexual dysfunctio... 9495707 - High-power potassium-titanyl-phosphate (ktp/532) laser vaporization prostatectomy: 24 h... 23218627 - Intermittent pneumatic compression for venous thromboembolism prophylaxis in total knee... 8284887 - Laser treatment of urethral condyloma: a five-year experience. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Journal of urology Volume: 172 ISSN: 0022-5347 ISO Abbreviation: J. Urol. Publication Date: 2004 Sep |
Date Detail:
|
Created Date: 2004-08-16 Completed Date: 2004-09-03 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0376374 Medline TA: J Urol Country: United States |
Other Details:
|
Languages: eng Pagination: 1017-20 Citation Subset: AIM; IM |
Affiliation:
|
Department of Urology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan. goya@kc.twmu.ac.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Ethanol / administration & dosage*, adverse effects Humans Injections / adverse effects Male Middle Aged Prostatic Hyperplasia / drug therapy* Quality of Life Retreatment Treatment Outcome Urethra |
| Chemical | |
Reg. No./Substance:
|
64-17-5/Ethanol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Transurethral holmium laser enucleation of the prostate versus transurethral electrocautery resectio...
Next Document: Clinical experiences with desmopressin for long-term treatment of nocturia.