Document Detail

Transurethral 2-microm laser in the treatment of urethral stricture.
MedLine Citation:
PMID:  19649639     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To evaluate the curative efficacy of transurethral 2-mum thulium laser urethrotomy in the treatment of urethral stricture. METHODS: Two hundred and thirty-eight patients suffering from urethral stricture, all male, aged 47.3 (36-58), underwent transurethral 2-mum thulium laser urethrotomy. The maximum flow rate (MFR), the international prostatic symptom score (IPSS) and the quality of life (QoL) were measured before operation, immediately following the removal of the catheter, and 3 and 6 months postoperatively. RESULTS: The surgery was performed for all the patients with no rectum injury, urine leakage or massive blood loss. All the patients got free urination immediately following the catheter removal with the mean MFR improved from (3.2 + or - 0.3) ml/s preoperatively to (16.7 + or - 3.1) ml/s, which kept steady to (18.7 + or - 2.9) and (19.2 + or - 2.8) ml/s, respectively 3 and 6 months after operation. IPSS significantly improved from 28.3 + or - 5.8 preoperatively to 7.1 + or - 1.9, 6.4 + or - 1.5 and 5.3 + or - 1.3, respectively when catheter removal and 3 and 6 months after operation. Also during the corresponding period, mean QoL improved from 5.4 + or - 1.1 to 1.1 + or - 0.3, 0.9 + or - 0.2 and 0.8 + or - 0.2. 195, patients got permanent uninterrupted urination without recurrence in the whole 6 months of follow-up. Forty-three patients got recurrence and seven patients encountered with incontinence 1-3 weeks (mean 13.8 days) after catheter removal, but they all got final cure after periodic urethral dilatation and physical exercise. CONCLUSIONS: Transurethral 2-mum thulium laser is safe and efficient in the treatment of urethral stricture.
Feng Fu Guo; Hua Lu; Guang Jian Wang; Shan Feng Tan; Xiang Fei He; Jian Ming Wang; Hong Jun Liu; Wen Bin Zhu
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Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2009-08-02
Journal Detail:
Title:  World journal of urology     Volume:  28     ISSN:  1433-8726     ISO Abbreviation:  World J Urol     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-08     Completed Date:  2010-07-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8307716     Medline TA:  World J Urol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  173-5     Citation Subset:  IM    
Department of Urology, Linyi People's Hospital, Jiefang Road No. 27 (East), Linyi, Shandong, China.
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MeSH Terms
Follow-Up Studies
Laser Therapy / instrumentation*,  methods
Lasers, Solid-State*
Middle Aged
Postoperative Complications / therapy
Quality of Life
Treatment Outcome
Urethral Stricture / surgery*
Urinary Incontinence / therapy
Reg. No./Substance:

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