Document Detail

Transudative malignant pleural effusions: prevalence and mechanisms.
MedLine Citation:
PMID:  9438397     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Malignant pleural effusions are classically exudative, though occasionally they can be transudative. We attempted to determine the prevalence of transudative malignant pleural effusions and to describe their clinical and radiographic characteristics. METHODS: We studied the medical records of 215 patients with malignant pleural effusion, which contained complete data on pleural fluid analysis for 171 of them. RESULTS: Eight cases of transudative malignant effusion were found. Seven of these eight patients had a concomitant disorder known to cause transudative pleural effusion. One patient had fluid overload due to renal failure, and another had been admitted earlier with congestive heart failure. Two patients had definite evidence of deep venous thrombosis, allowing us to postulate pulmonary embolism as a factor contributing to transudation. Three patients had CT evidence of superior vena cava obstruction. Only one patient had no known associations with causes of transudative effusion. CONCLUSION: Malignant pleural effusions were transudative in 5% of our patients. In all except one patient, some evidence suggested the concomitant presence of a transudative state.
M Ashchi; J Golish; P Eng; P O'Donovan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  91     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-01-27     Completed Date:  1998-01-27     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  23-6     Citation Subset:  AIM; IM    
Division of Cardiology, University of Connecticut, Hartford Hospital, USA.
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MeSH Terms
Aged, 80 and over
Creatinine / blood
Exudates and Transudates
L-Lactate Dehydrogenase / metabolism
Pleural Effusion, Malignant / enzymology,  metabolism,  physiopathology*
Proteins / metabolism
Serum Albumin / metabolism
Reg. No./Substance:
0/Proteins; 0/Serum Albumin; 60-27-5/Creatinine; EC Dehydrogenase

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