Document Detail


Transtympanic gentamicin perfusion for the treatment of Meniere's disease.
MedLine Citation:
PMID:  12391619     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Meniere's syndrome is defined as the clinical disorder associated with the histopathological finding of endolymphatic hydrops (ELH). Clinically, Meniere's syndrome includes the following features: recurrent, spontaneous episodic vertigo; hearing loss; aural fullness; and tinnitus. Recognized causes of Meniere's syndrome include: 1) idiopathic, also known as Meniere's disease; 2) posttraumatic, following head injury or ear surgery; 3) post-infectious or delayed-onset Meniere's syndrome following a viral infection, usually mumps or measles; 4) late stage syphilitic; 5) classic Cogan's syndrome with episodic vertigo, hearing loss, interstitial keratitis, without syphilis; 6) variant Cogan's syndrome with episodic vertigo, hearing loss, uveitis or other ocular inflammation and without syphilis. Although Meniere's disease is by far the most common cause of Meniere's syndrome and the terms are often used interchangeably, it should be remembered that a patient has an idiopathic etiology only when the known causes have been excluded.
Authors:
Mitchell K Schwaber
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Otolaryngologic clinics of North America     Volume:  35     ISSN:  0030-6665     ISO Abbreviation:  Otolaryngol. Clin. North Am.     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-10-23     Completed Date:  2003-01-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0144042     Medline TA:  Otolaryngol Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  287-95, vi     Citation Subset:  IM    
Affiliation:
Nashville EAR Institute, 4230 Harding Rd #803, Nashville, TN 37205, USA.
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MeSH Terms
Descriptor/Qualifier:
Administration, Topical
Anti-Bacterial Agents / administration & dosage,  therapeutic use*
Gentamicins / administration & dosage,  therapeutic use*
Humans
Meniere Disease / drug therapy*,  surgery
Otologic Surgical Procedures / methods
Tympanic Membrane
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Gentamicins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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