Document Detail

Transthoracic needle aspiration biopsy. Review of 233 cases.
MedLine Citation:
PMID:  3336947     Owner:  NLM     Status:  MEDLINE    
In 233 cases in which transthoracic needle aspiration was done at the Mayo Clinic from 1980 through 1983, the cytology slides, tissue fragments and patient histories were reviewed; the original and review diagnoses were compared and correlated with the subsequent clinical course. In most cases, the procedure was performed with an 18-gauge needle under fluoroscopic guidance, primarily in cases with suspected malignant masses that were considered to be not surgically resectable. In 70% of the cases, there was a history of malignancy, and 82% of the malignant lesions were of extrapulmonary origin. Correlation of the original diagnosis with the clinical course yielded 70% (164 cases) true positives, 6% (14 cases) true negatives, 16% (37 cases) false negatives, 0% false positives and 8% (18 cases) indeterminants. In none of the false-negative cases was the slide subsequently read as positive in a blind review. Of the true-positive cases, 12% had positive tissue fragments only, 37% had positive cytology smears only, and 51% had both positive smears and fragments. In 32% of the cases, there were radiologically demonstrable pneumothoraces, and in 12%, placement of a chest tube was required. Hemoptysis occurred in less than 5% of the cases. In summary, transthoracic needle biopsy provides an efficient way to accurately obtain diagnostic tissue, with acceptable minor complications.
R W Simpson; D A Johnson; L E Wold; J R Goellner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta cytologica     Volume:  32     ISSN:  0001-5547     ISO Abbreviation:  Acta Cytol.     Publication Date:    1988 Jan-Feb
Date Detail:
Created Date:  1988-02-25     Completed Date:  1988-02-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370307     Medline TA:  Acta Cytol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  101-4     Citation Subset:  IM    
Section of Surgical Pathology, Mayo Clinic, Rochester, MN 55905.
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MeSH Terms
Aged, 80 and over
Biopsy, Needle / methods
Carcinoma / classification,  diagnosis,  pathology*
Middle Aged
Thoracic Neoplasms / diagnosis,  pathology*,  secondary

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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