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Transthoracic impedance for the monitoring of quality of manual chest compression during cardiopulmonary resuscitation.
MedLine Citation:
PMID:  22828357     Owner:  NLM     Status:  Publisher    
OBJECTIVE: The quality of cardiopulmonary resuscitation (CPR), especially adequate compression depth, is associated with return of spontaneous circulation (ROSC) and is therefore recommended to be measured routinely. In the current study, we investigated the relationship between changes of transthoracic impedance (TTI) measured through the defibrillation electrodes, chest compression depth and coronary perfusion pressure (CPP) in a porcine model of cardiac arrest. METHODS: In 14 male pigs weighing between 28 to 34kg, ventricular fibrillation (VF) was electrically induced and untreated for 6minutes. Animals were randomized to either optimal or suboptimal chest compression group. Optimal depth of manual compression in 7 pigs was defined as a decrease of 25% (50mm) in anterior posterior diameter of the chest, while suboptimal compression was defined as 70% of the optimal depth (35mm). After 2minutes of chest compression, defibrillation was attempted with a 120-J rectilinear biphasic shock. RESULTS: There were no differences in baseline measurements between groups. All animals had ROSC after optimal compressions; this contrasted with suboptimal compressions, after which only 2 of the animals had ROSC (100% vs. 28.57%, p=0.021). The correlation coefficient was 0.89 between TTI amplitude and compression depth (p<0.001), 0.83 between TTI amplitude and CPP (p<0.001). CONCLUSION: Amplitude change of TTI was correlated with compression depth and CPP in this porcine model of cardiac arrest. The TTI measured from defibrillator electrodes, therefore has the potential to serve as an indicator to monitor the quality of chest compression and estimate CPP during CPR.
Hehua Zhang; Zhengfei Yang; Zitong Huang; Bihua Chen; Lei Zhang; Heng Li; Baoming Wu; Tao Yu; Yongqin Li
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-21
Journal Detail:
Title:  Resuscitation     Volume:  -     ISSN:  1873-1570     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0332173     Medline TA:  Resuscitation     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier Ireland Ltd.
Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, China.
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