Document Detail

Transthoracic electrical bioimpedence cardiac output: comparison with multigated equillibrium radionuclide cardiography.
MedLine Citation:
PMID:  20229061     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Thoracic electrical bioimpedance (TEB) for measuring cardiac output (CO) is being explored increasingly as an alternative to pulmonary artery catheter. The major advantage of this technology is that it is non-invasive and easy to perform. Several studies have compared it to thermodilution cardiac output using PA catheter, with variable correlation. Multigated radionuclide equilibrium cardiography (RNEC) method of cardiac output measurement is known to be reliable. OBJECTIVE: To compare cardiac output measured by thoracic electrical bioimpdenace with that measured by multigated radionuclide equilibrium cardiography. PATIENTS AND METHODS: CO studies were performed sequentially at a single sitting by TEB and RNEC methods among patients with cardiac symptoms referred for radionuclide study as part of their evaluation. TEB CO was measured by placing two pairs of electrodes on either side of neck and two other pairs on either side of the lower chest. Stroke volume was estimated from the sequential changes in transthoracic electrical bioimpedance induced by rhythmic aortic blood flow, using Kubicek equation. RNEC-CO was measured by intravenous injection of radio-active Technitium-tagged RBCs followed by ECG gated blood pool imaging over the chest (MUGA study). Bland-Altman analysis was used to compare the measurements. RESULTS: A total of 32 subjects with proven or suspected ischemic heart disease, but without overt cardiac failure, edema or arrhythmias were studied (M:F::26:6; mean age: 48 +/- 12 years). The mean TEB-CO was 3.54 +/- 1.052 l/min and mean RNEC-CO was 3.907 +/- 0.952 l/min. Correlation coefficient (r) for these measurements was 0.67 (p < 0.01), with bias: -0.421 l/min; precision: 1.557 l/min; and percentage error of measurement: 42.35%. CONCLUSIONS: This study observed a moderate correlation between TEB and RNEC methods of CO measurement. Further studies are indicated to explore the relative utility of TEB in comparison with RNEC as well as other methods of CO measurement before considering its use in patients with ischemic heart disease.
Arunodaya R Gujjar; K Muralidhar; Abhijit Bhandopadhyaya; T N Sathyaprabha; P Janaki; B K Mahalla; Ratan Gupta; Sanjay Banakal; P S Jairaj
Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-03-13
Journal Detail:
Title:  Journal of clinical monitoring and computing     Volume:  24     ISSN:  1573-2614     ISO Abbreviation:  J Clin Monit Comput     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-30     Completed Date:  2010-08-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9806357     Medline TA:  J Clin Monit Comput     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  155-9     Citation Subset:  IM    
National Institute of Mental Health and Neurosciences, Bangalore, 560029, India.
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MeSH Terms
Aged, 80 and over
Cardiac Output*
Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography / methods*
Cardiography, Impedance / methods*
Middle Aged
Reproducibility of Results
Sensitivity and Specificity
Ventricular Dysfunction, Left / diagnosis*
Young Adult

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